Microbiological contamination of raw materials for large-volume parenterals

Endotoxin Contamination of Large Volume Parenterals as Detected by Limulus Amebocyte Lysate as an Alternative to Rabbit Pyrogen Test

The possibility of replacing the rabbit pyrogen test by the Limulus Amebocyte lysate (LAL) test, as a final release test for Large Volume Parenterals (LVPs) was investigated. The sensitivity and specificity of the LAL test and rabbit pyrogen assay were studied by means of artificially contaminated parenterals. Various LVPs (mostly containing electrolytes) were spiked with 0.5 and 5 EUlml o...

Effect of chicken raw materials on physicochemical and microbiological properties of ‎mechanically deboned chicken meat

Excessive consumption of red meat is associated with various diseases including coronary heart diseases and cancer. Lower health-related problems of chicken meat, consumption of chicken meat, and mechanically deboned chicken meat (MDCM) have been increased due to their cheaper prices. Thereby, chemical, microbial, and physical causes of chicken meat losses and the safety aspects are needed to b...

endotoxin contamination of large volume parenterals as detected by limulus amebocyte lysate as an alternative to rabbit pyrogen test

the possibility of replacing the rabbit pyrogen test by the limulus amebocyte lysate (lal) test, as a final release test for large volume parenterals (lvps) was investigated. the sensitivity and specificity of the lal test and rabbit pyrogen assay were studied by means of artificially contaminated parenterals. various lvps (mostly containing electrolytes) were spiked with 0.5 and 5 eulml of e.c...

Risk Profile on the Microbiological Contamination of Fruits and Vegetables Eaten Raw

Microbiological Contamination of Hospital Air

GREENE, V. W. (University of Minnesota, Minneapolis), D. VESLEY, R. G. BOND, AND G. S. MICHAELSEN. Microbiological contamination of hospital air. II. Qualitative studies. Appl. Microbiol. 10:567-571. 1962.-Over 10,000 airborne microorganisms, isolated from various areas of two hospitals, were characterized according to colonial and microscopic morphology and certain physiological reactions, inc...